SCHEMBL7002479

SCHEMBL7002479

C[Si](C)(C)CCOCc1nc(C=O)c[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4900302 0.77 HCAR2 (0.33)
SCHEMBL27127022 0.75 HCAR2 (0.33)
SCHEMBL25257427 0.75
SCHEMBL12489591 0.74
SCHEMBL3945997 0.73
SCHEMBL28009095 0.73
SCHEMBL8799687 0.73 TSHR (0.46)
SCHEMBL31378504 0.72
SCHEMBL949418 0.71
SCHEMBL7001110 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118103362-A Herbicidal imidazole compounds 先正达农作物保护股份公司 2024-05-28 CN disclosed
EP-1286967-A1 CYCLOHEXANE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS MERCK SHARP &amp; DOHME LTD. (GB) 2003-03-05 EP disclosed
WO-2001087838-A1 CYCLOHEXANE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS MERCK SHARP & DOHME LIMITED (GB) 2001-11-22 WO disclosed