Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 13/20 | 0.80 |
| ▸ | AVPR1A | P37288 | 12/20 | 0.80 |
| ▸ | OXTR | P30559 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314637 | 0.92 | AVPR2 (0.88) | AVPR2AVPR1AOXTR | |
| SCHEMBL8317046 | 0.89 | AVPR2 (0.85) | AVPR2AVPR1AOXTR | |
| SCHEMBL7339573 | 0.89 | AVPR2 (1.00) | AVPR2AVPR1AOXTR | |
| SCHEMBL5738817 | 0.88 | AVPR2 (1.00) | AVPR2AVPR1AOXTR | |
| SCHEMBL8313381 | 0.87 | AVPR2 (1.00) | AVPR2AVPR1AOXTR | |
| SCHEMBL8317230 | 0.87 | AVPR2 (0.80) | AVPR2AVPR1AOXTR | |
| SCHEMBL8314641 | 0.87 | AVPR2 (0.88) | AVPR2AVPR1AOXTR | |
| SCHEMBL8317084 | 0.87 | AVPR2 (1.00) | AVPR2AVPR1AOXTR | |
| SCHEMBL5739957 | 0.86 | AVPR2 (0.70) | AVPR2AVPR1A | |
| SCHEMBL7341103 | 0.86 | AVPR2 (0.90) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1330653-C | 3-methylamide derivatives of 5H-pyrrolo [2,1,-C] [1,4]-benzodiazepines | AMERICAN HOME PROD (US) | 2007-08-08 | — | — | CN | disclosed |
| EP-1021444-B1 | 3-CARBOXAMIDE DERIVATIVES OF 5H-PYRROLO[2,1-c][1,4]-BENZODIAZEPINES | WYETH CORP (US) | 2003-09-24 | — | — | EP | disclosed |
| EP-1021444-A1 | 3-CARBOXAMIDE DERIVATIVES OF 5H-PYRROLO[2,1-c][1,4]-BENZODIAZEPINES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-07-26 | — | — | EP | disclosed |
| CN-1234801-A | 3-carboxamide derivatives of 5H-pyrrolo [2, 1-C ] [1,4] -benzodiazepine * | AMERICAN HOME PROD (US) | 1999-11-10 | — | — | CN | disclosed |
| WO-1998020011-A1 | 3-CARBOXAMIDE DERIVATIVES OF 5H-PYRROLO[2,1-c][1,4]-BENZODIAZEPINES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-05-14 | — | — | WO | disclosed |