Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.45 |
| ▸ | FLT1 | P17948 | 7/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310388 | 0.90 | FLT1 (0.48) | EGFRFLT1ADORA2BADORA3 | |
| SCHEMBL6302174 | 0.89 | EGFR (0.44) | EGFRFLT1ADORA2AADORA2BMKNK1 | |
| SCHEMBL6623990 | 0.89 | FLT1 (0.47) | EGFRFLT1 | |
| SCHEMBL6303870 | 0.88 | EGFR (0.49) | EGFRFLT1 | |
| SCHEMBL6302403 | 0.86 | FLT1 (0.51) | EGFRFLT1ADORA2AADORA2B | |
| SCHEMBL6302384 | 0.86 | FLT1 (0.51) | EGFRFLT1ADORA2AADORA2B | |
| SCHEMBL6309330 | 0.86 | FLT1 (0.51) | EGFRFLT1ADORA2AADORA2B | |
| SCHEMBL6301857 | 0.85 | FLT1 (0.49) | EGFRFLT1ADORA2AADORA2BADORA3 | |
| SCHEMBL6301850 | 0.85 | FLT1 (0.49) | EGFRFLT1ADORA2AADORA2BADORA3 | |
| SCHEMBL6302228 | 0.85 | EGFR (0.49) | EGFRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287001-A1 | THIOPHENE DERIVATIVES USEFUL AS ANTICANCER AGENTS | Pfizer Products Inc. (US) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001094353-A1 | THIOPHENE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PRODUCTS INC. (US) | 2001-12-13 | — | — | WO | disclosed |