Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675594 | 0.82 | ESR1 (0.45) | KMT2AATMNPSR1ALDH1A1TSHR | |
| SCHEMBL11311947 | 0.82 | ESR1 (0.45) | KMT2AATMNPSR1ALDH1A1TSHR | |
| SCHEMBL6287047 | 0.82 | ESR1 (0.45) | KMT2AATMNPSR1ALDH1A1TSHR | |
| SCHEMBL8954559 | 0.81 | KMT2A (0.39) | KMT2AATMNPSR1ALDH1A1TSHR | |
| SCHEMBL4592121 | 0.81 | ESR1 (0.38) | KMT2AATMNPSR1ALDH1A1TSHR | |
| SCHEMBL4592118 | 0.80 | ESR1 (0.40) | KMT2AATMNPSR1ALDH1A1TSHR | |
| SCHEMBL2683898 | 0.77 | GAA (0.38) | KMT2AATMNPSR1ALDH1A1TSHR | |
| SCHEMBL8015097 | 0.77 | ESR1 (0.42) | KMT2AATMNPSR1ALDH1A1TSHR | |
| SCHEMBL17627921 | 0.77 | KMT2A (0.37) | KMT2AATMNPSR1ALDH1A1TSHR | |
| SCHEMBL39424 | 0.77 | KMT2A (0.37) | KMT2AATMNPSR1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282630-A1 | HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS | Ciba SC Holding AG (CH) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001090113-A1 | HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-11-29 | — | — | WO | disclosed |