Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000591 | 0.85 | CCR1 (0.62) | CCR1S1PR5FPR3GPR65GPR35 | |
| SCHEMBL7000018 | 0.85 | CCR1 (0.53) | CCR1S1PR5FPR3GPR65GPR35 | |
| SCHEMBL7000803 | 0.82 | CCR1 (0.40) | CCR1S1PR5CCR3FPR3GPR65 | |
| SCHEMBL7144980 | 0.82 | CCR1 (0.61) | CCR1S1PR5FPR3GPR65GPR35 | |
| SCHEMBL6997000 | 0.79 | CCR1 (0.49) | CCR1S1PR5FPR3GPR65GPR35 | |
| SCHEMBL5055476 | 0.77 | CCR1 (0.75) | CCR1FPR3GPR65GPR35 | |
| SCHEMBL5055487 | 0.77 | CCR1 (0.75) | CCR1FPR3GPR65GPR35 | |
| SCHEMBL5055470 | 0.77 | CCR1 (0.75) | CCR1FPR3GPR65GPR35 | |
| SCHEMBL7004433 | 0.77 | CCR1 (0.49) | CCR1MEN1KMT2AFPR3GPR65 | |
| SCHEMBL6994339 | 0.77 | CCR1 (0.48) | CCR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326867-A2 | BRIDGED PIPERAZINE DERIVATIVES | Pfizer Products Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032901-A2 | BRIDGED PIPERAZINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2002-04-25 | — | — | WO | disclosed |