Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.59 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827646 | 0.93 | PDE5A (0.69) | PDE5APDE3BPDE3A | |
| SCHEMBL5827374 | 0.92 | PDE5A (0.62) | PDE5A | |
| SCHEMBL5827295 | 0.91 | PDE5A (0.68) | PDE5A | |
| SCHEMBL5827907 | 0.90 | PDE5A (0.65) | PDE5APDE3BPDE3A | |
| SCHEMBL5827835 | 0.90 | PDE5A (0.61) | PDE5APDE3BPDE3A | |
| SCHEMBL5827397 | 0.90 | PDE5A (0.59) | PDE5APDE3BPDE3A | |
| SCHEMBL5827400 | 0.90 | PDE5A (0.58) | PDE5A | |
| SCHEMBL5827313 | 0.89 | PDE5A (0.69) | PDE5APDE3BPDE3A | |
| SCHEMBL5827844 | 0.89 | PDE5A (0.69) | PDE5A | |
| SCHEMBL5827489 | 0.89 | PDE5A (0.58) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198464-B1 | 8-PHENYL-6,9-DIHYDRO-[1,2,4]TRIAZOLO[3,4-i]PURIN-5-ONE DERIVATIVES | ALMIRALL PRODESFARMA SA (ES) | 2003-10-08 | — | — | EP | disclosed |