Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3779386 | 0.92 | ABCC4 (0.46) | ABCC4MAPTFOLH1CHRM1AKR1A1 | |
| SCHEMBL5494036 | 0.88 | ABCC4 (0.43) | ABCC4MAPTFOLH1CHRM1AKR1A1 | |
| SCHEMBL5975672 | 0.88 | MAPT (0.48) | ABCC4MAPTFOLH1CHRM1AKR1A1 | |
| SCHEMBL4404302 | 0.86 | MAPT (0.42) | ABCC4MAPTFOLH1CHRM1AKR1A1 | |
| SCHEMBL4404306 | 0.86 | MAPT (0.42) | ABCC4MAPTFOLH1CHRM1AKR1A1 | |
| SCHEMBL4016679 | 0.85 | MAPT (0.50) | ABCC4MAPTFOLH1CHRM1AKR1A1 | |
| SCHEMBL4015850 | 0.83 | MAPT (0.54) | ABCC4MAPTFOLH1CHRM1AKR1A1 | |
| SCHEMBL3804921 | 0.83 | MAPT (0.54) | ABCC4MAPTFOLH1CHRM1AKR1A1 | |
| SCHEMBL21439803 | 0.83 | MAPT (0.54) | ABCC4MAPTFOLH1CHRM1AKR1A1 | |
| SCHEMBL3103111 | 0.83 | MAPT (0.54) | ABCC4MAPTFOLH1CHRM1AKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363912-A1 | NOVEL SUBSTITUTED IMIDAZOTRIAZINONES | Bayer Aktiengesellschaft (DE) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002068423-A1 | NOVEL SUBSTITUTED IMIDAZOTRIAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-06 | — | — | WO | disclosed |