Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5234930 | 0.99 | DPP4 (0.53) | DPP4MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL5236656 | 0.91 | DPP4 (0.44) | DPP4MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL5237954 | 0.90 | MEN1 (0.43) | DPP4MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL5239292 | 0.85 | DPP4 (0.40) | DPP4MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL5236012 | 0.84 | DPP4 (0.41) | DPP4MEN1KMT2ALMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL5238660 | 0.83 | DPP4 (0.61) | DPP4LMNACYP1A2CYP3A4KDM4E | |
| SCHEMBL5240287 | 0.82 | MEN1 (0.43) | DPP4MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL6106926 | 0.81 | DPP4 (0.39) | DPP4MEN1KMT2ALMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL5240391 | 0.80 | DPP4 (0.50) | DPP4CYP1A2KDM4EALOX15TSHR | |
| Hydrochloric Acid SCHEMBL5240578 | 0.80 | DPP4 (0.50) | DPP4CYP1A2KDM4EALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355886-A1 | FUSED HETEROCYCLIC COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002062764-A1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-08-15 | — | — | WO | disclosed |