SCHEMBL7004084

SCHEMBL7004084

Cc1ccccc1Nc1ccc(-c2ccc(N)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.58
KDM4E B2RXH2 3/20 0.58
HSD17B10 Q99714 2/20 0.58
TP53 P04637 2/20 0.58
ALOX15 P16050 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
APP P05067 1/20 0.58
HPGD P15428 1/20 0.58
SNCA P37840 1/20 0.58
BLM P54132 1/20 0.58
ALDH1A1 P00352 6/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
MAPK1 P28482 1/20 0.54
TDP1 Q9NUW8 5/20 0.50
HTT P42858 4/20 0.50
GAA P10253 4/20 0.50
CYP3A4 P08684 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7027050 0.94 MAPT (0.64) MAPTKDM4EHSD17B10TP53ALOX15
SCHEMBL512863 0.90 MAPT (0.48) MAPTKDM4EHSD17B10TP53ALOX15
SCHEMBL7007661 0.88 MAPT (0.51) MAPTKDM4EHSD17B10TP53ALOX15
SCHEMBL17858148 0.86 PTGER4 (0.49) MAPTKDM4EHSD17B10TP53ALOX15
SCHEMBL7007115 0.85 MAPT (0.44) MAPTKDM4EHSD17B10TP53ALOX15
SCHEMBL29653984 0.84 MAPT (0.54) MAPTKDM4EHSD17B10TP53ALOX15
SCHEMBL108882 0.84 MAPT (0.54) MAPTKDM4EHSD17B10TP53ALOX15
SCHEMBL24260090 0.80 MAPK10 (0.47) MAPTTP53SMN1; SMN2ALDH1A1TDP1
SCHEMBL31454751 0.80 MAPT (0.78) MAPTKDM4EHSD17B10TP53ALOX15
SCHEMBL7974344 0.79 MAPT (0.55) MAPTKDM4EHSD17B10TP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0995786-B1 Electrochromic device NIPPON MITSUBISHI OIL CORP (JP) 2003-01-08 EP disclosed
US-6208452-B1 HAS AN ION CONDUCTIVE LAYER OBTAINED BY CURING A COMPOSITION COMPRISING A BIPYRIDINIUM COMPOUND, A SPECIFIC AMINE COMPOUND AND A PRECURSOR COMPONENT OF A POLYMERIC SOLID ELECTROLYTE DISPOSED BETWEEN TWO ELECTRICALLY CONDUCTIVE SUBSTRATES NIPPON MITSUBISHI OIL CORPORATION (JP) 2001-03-27 US disclosed
US-6203154-B1 MULTILAYER NIPPON MITSUBISHI OIL CORPORATION (JP) 2001-03-20 US disclosed
EP-1041425-A1 ELECTROCHROMIC ELEMENT Nippon Mitsubishi Oil Corporation (JP) 2000-10-04 EP disclosed
EP-0995786-A1 Electrochromic device Nippon Mitsubishi Oil Corporation (JP) 2000-04-26 EP disclosed