Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.40 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.40 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.40 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008093 | 0.92 | STAT3 (0.48) | STAT3PIM1IRAK1CAMK2BCAMK2G | |
| SCHEMBL7007313 | 0.85 | TSHR (0.47) | STAT3PIM1IRAK1CAMK2BCAMK2G | |
| SCHEMBL7005450 | 0.84 | STAT3 (0.48) | STAT3PIM1IRAK1CAMK2BCAMK2G | |
| SCHEMBL7005366 | 0.82 | HTT (0.40) | STAT3PIM1IRAK1CAMK2BCAMK2G | |
| SCHEMBL7005460 | 0.81 | PIM1 (0.41) | STAT3PIM1IRAK1CAMK2BCAMK2G | |
| SCHEMBL7012730 | 0.81 | HTT (0.47) | STAT3PIM1IRAK1CAMK2BCAMK2G | |
| SCHEMBL7009121 | 0.80 | PIM1 (0.37) | STAT3PIM1IRAK1CAMK2BCAMK2G | |
| SCHEMBL7005266 | 0.78 | STAT3 (0.46) | STAT3PIM1IRAK1CAMK2BCAMK2G | |
| SCHEMBL7008762 | 0.76 | STAT3 (0.41) | STAT3PIM1IRAK1CAMK2BCAMK2G | |
| SCHEMBL7010692 | 0.75 | PIM1 (0.40) | STAT3PIM1IRAK1CAMK2BCAMK2G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787720-B1 | PYRIDONECARBOXYLATE DERIVATIVE OR SALT THEREOF AND ANTIBACTERIAL CONTAINING THE SAME AS ACTIVE INGREDIENT | WAKUNAGA SEIYAKU KK (JP) | 2003-07-16 | — | — | EP | disclosed |
| US-5910498-A | NOVEL COMPOUNDS HAVING REDUCED CYTOTOXICITY, PHOTOTOXICITY; TREATING BACTERIAL AND VIRAL INFECTIONS | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1999-06-08 | — | — | US | disclosed |