Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.42 |
| ▸ | TOP1 | P11387 | 8/20 | 0.36 |
| ▸ | TOP2A | P11388 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8180660 | 0.89 | PIM1 (0.52) | PIM1TOP1TOP2AALDH1A1KDM4E | |
| Methylamine SCHEMBL7004401 | 0.88 | PIM1 (0.51) | PIM1TOP1TOP2AALDH1A1KDM4E | |
| SCHEMBL7010438 | 0.82 | PIM1 (0.47) | PIM1TOP1TOP2AALDH1A1KDM4E | |
| SCHEMBL7013639 | 0.77 | TOP1 (0.53) | PIM1TOP1TOP2AALDH1A1KDM4E | |
| SCHEMBL7004402 | 0.76 | TOP1 (0.49) | PIM1TOP1TOP2AALDH1A1KDM4E | |
| SCHEMBL7006672 | 0.75 | CYP3A4 (0.34) | PIM1TOP1TOP2AALDH1A1KDM4E | |
| SCHEMBL7012923 | 0.75 | TOP1 (0.46) | PIM1TOP1TOP2AALDH1A1KDM4E | |
| SCHEMBL7015797 | 0.75 | TOP1 (0.41) | PIM1TOP1TOP2AALDH1A1POLB | |
| SCHEMBL7014048 | 0.75 | TOP1 (0.46) | PIM1TOP1TOP2AALDH1A1KDM4E | |
| SCHEMBL7007296 | 0.75 | TOP1 (0.46) | PIM1TOP1TOP2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945435-B1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMA CO LTD (JP) | 2003-08-13 | — | — | EP | disclosed |
| EP-0945435-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |