Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.58 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647318 | 1.00 | ESR1 (0.58) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL10689770 | 0.86 | ESR1 (0.46) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL8065687 | 0.83 | ESR1 (0.43) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL581164 | 0.83 | ESR1 (0.43) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL870710 | 0.83 | ESR1 (0.43) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL8468614 | 0.82 | ESR1 (0.59) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1274832 | 0.81 | ESR1 (0.49) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL17491275 | 0.81 | ESR1 (0.61) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL9230479 | 0.81 | ESR1 (0.61) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL9222985 | 0.81 | ESR1 (0.61) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282630-A1 | HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS | Ciba SC Holding AG (CH) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001090113-A1 | HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-11-29 | — | — | WO | disclosed |