Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.75 |
| ▸ | CCR7 | P32248 | 4/20 | 0.49 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3857492 | 0.89 | CXCR2 (0.78) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3853081 | 0.86 | CXCR2 (0.81) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3856676 | 0.86 | CXCR2 (0.81) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3853077 | 0.86 | CXCR2 (0.81) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3849356 | 0.86 | CXCR2 (1.00) | CXCR2CCR7 | |
| SCHEMBL3850612 | 0.86 | CXCR2 (1.00) | CXCR2CCR7 | |
| SCHEMBL3849366 | 0.86 | CXCR2 (1.00) | CXCR2CCR7 | |
| SCHEMBL3850892 | 0.85 | CXCR2 (0.83) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3850323 | 0.85 | CXCR2 (0.98) | CXCR2CCR7 | |
| SCHEMBL3850313 | 0.85 | CXCR2 (0.98) | CXCR2CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259512-B1 | PTERIDINE COMPOUNDS FOR THE TREATMENT OF PSORIASIS | ASTRAZENECA AB (SE) | 2003-09-24 | — | — | EP | claimed |