Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 12/20 | 0.44 |
| ▸ | PPARA | Q07869 | 10/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4826826 | 0.82 | KDM4E (0.55) | KDM4EPPARGPPARAHPGDTP53 | |
| SCHEMBL4823431 | 0.81 | KDM4E (0.54) | KDM4EPPARGPPARAHPGDTP53 | |
| SCHEMBL10165837 | 0.74 | KDM4E (0.74) | KDM4EPPARGPPARAHPGDTP53 | |
| SCHEMBL14260722 | 0.74 | KDM4E (0.74) | KDM4EPPARGPPARAHPGDTP53 | |
| SCHEMBL13694666 | 0.73 | KDM4E (0.61) | KDM4EPPARGPPARAHPGDTP53 | |
| SCHEMBL2407014 | 0.73 | HDAC1 (0.52) | KDM4EPPARGPPARATP53POLB | |
| SCHEMBL2406457 | 0.73 | POLB (0.52) | KDM4EPPARGPPARAHPGDTP53 | |
| SCHEMBL2930640 | 0.72 | KDM4E (0.74) | KDM4EPPARGPPARAHPGDTP53 | |
| SCHEMBL893027 | 0.71 | KDM4E (1.00) | KDM4EPPARGPPARAHPGDTP53 | |
| SCHEMBL6437060 | 0.71 | KDM4E (0.72) | KDM4EPPARGPPARAHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343753-A2 | ANTIMICROBIAL AGENTS | De Novo Pharmaceuticals Ltd. (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002050081-A2 | ANTIMICROBIAL AGENTS | DE NOVO PHARMACEUTICALS LTD (GB) | 2002-06-27 | — | — | WO | disclosed |