Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.65 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.65 |
| ▸ | CDC25B | P30305 | 4/20 | 0.65 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.60 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.59 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12008432 | 1.00 | PPARG (1.00) | PPARGMAPTMAPK1ATMPTPN1 | |
| SCHEMBL12008475 | 0.93 | PPARG (0.88) | PPARGMAPTMAPK1ATMPTPN1 | |
| SCHEMBL17319255 | 0.89 | PPARG (0.80) | PPARGMAPTMAPK1ATMPTPN1 | |
| SCHEMBL10492235 | 0.88 | PPARG (0.79) | PPARGMAPTMAPK1ATMKMT2A | |
| SCHEMBL10492231 | 0.88 | PPARG (0.79) | PPARGMAPTMAPK1ATMKMT2A | |
| SCHEMBL12008533 | 0.88 | PPARG (0.78) | PPARGMAPTMAPK1ATMPTPN1 | |
| SCHEMBL17319556 | 0.87 | PPARG (0.77) | PPARGMAPTMAPK1ATMPTPN1 | |
| SCHEMBL12008790 | 0.86 | PPARG (0.76) | PPARGMAPTCISD1MAOAMAP3K5 | |
| SCHEMBL4416909 | 0.84 | PPARG (0.72) | PPARGMAPTMAPK1ATMPTPN1 | |
| SCHEMBL4416907 | 0.84 | PPARG (0.72) | PPARGMAPTMAPK1ATMPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1128832-A4 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING VIRAL INFECTIONS AND ASSOCIATED DISEASES | VIROPHARMA INC (US) | 2003-03-05 | — | — | EP | disclosed |
| EP-1128832-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING VIRAL INFECTIONS AND ASSOCIATED DISEASES | Viropharma Incorporated (US) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000010573-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING VIRAL INFECTIONS AND ASSOCIATED DISEASES | VIROPHARMA INCORPORATED (US) | 2000-03-02 | — | — | WO | disclosed |