Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.88 |
| ▸ | PDE5A | O76074 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576451 | 0.96 | KMT2A (0.80) | KMT2APDE5AALDH1A1GAACYP2D6 | |
| SCHEMBL3587341 | 0.94 | KMT2A (1.00) | KMT2APDE5AALDH1A1GAACYP2D6 | |
| SCHEMBL6441707 | 0.94 | KMT2A (1.00) | KMT2APDE5AALDH1A1GAACYP2D6 | |
| SCHEMBL6441696 | 0.93 | KMT2A (0.98) | KMT2APDE5AALDH1A1GAACYP2D6 | |
| Hydrochloric Acid SCHEMBL6386723 | 0.93 | KMT2A (0.98) | KMT2APDE5AALDH1A1GAACYP2D6 | |
| Hydrochloric Acid SCHEMBL6442412 | 0.93 | KMT2A (0.98) | KMT2APDE5AALDH1A1GAACYP2D6 | |
| Hydrochloric Acid SCHEMBL7388188 | 0.90 | KMT2A (0.92) | KMT2APDE5AALDH1A1GAACYP2D6 | |
| SCHEMBL6444862 | 0.87 | KMT2A (0.66) | KMT2APDE5AALDH1A1CYP2D6 | |
| SCHEMBL6442764 | 0.87 | KMT2A (0.66) | KMT2APDE5AALDH1A1GAACYP2D6 | |
| SCHEMBL6443105 | 0.86 | KMT2A (0.64) | KMT2APDE5AALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305314-A1 | CRYSTALLINE THERAPEUTIC AGENT | Pfizer Limited (GB) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002010171-A1 | CRYSTALLINE THERAPEUTIC AGENT | PFIZER LIMITED (GB) | 2002-02-07 | — | — | WO | disclosed |