Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.37 |
| ▸ | WNT3A | P56704 | 2/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29739347 | 1.00 | MAPT (0.48) | MAPTGAAKDM4ESMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL30774268 | 0.98 | MAPT (0.52) | MAPTGAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL655314 | 0.88 | MAPT (0.52) | MAPTGAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL266080 | 0.84 | PRKCI (0.49) | MAPTGAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL29739511 | 0.84 | PRKCI (0.49) | MAPTGAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL3838626 | 0.81 | MAPT (0.38) | MAPTGAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL22239364 | 0.78 | PRKCI (0.47) | MAPTGAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL8758775 | 0.78 | CTNNB1 (0.41) | KCNH2CTNNB1WNT3ACLK1DYRK1A | |
| SCHEMBL12526764 | 0.78 | KCNH2 (0.38) | KCNH2CTNNB1WNT3ACLK1DYRK1A | |
| SCHEMBL20330514 | 0.77 | PRKCI (0.46) | MAPTGAAKDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119541903-A | Method for identifying effectiveness of gastrodia elata extract in preventing and treating parkinsonism | 中国农业科学院农产品加工研究所 | 2025-02-28 | — | — | CN | claimed |
| CN-110551091-B | Asymmetric preparation method and application of 7-amino chroman compounds | 中国科学院上海有机化学研究所 | 2023-01-31 | — | — | CN | claimed |
| CN-110551091-A | Asymmetric preparation method and application of 7-amino chroman compounds | SHANGHAI INST ORGANIC CHEMISTRY CAS | 2019-12-10 | — | — | CN | claimed |
| CN-119541903-B | Method for identifying effectiveness of gastrodia elata extract in preventing and treating parkinsonism | 中国农业科学院农产品加工研究所 | 2025-06-13 | — | — | CN | disclosed |
| CN-119541903-A | Method for identifying effectiveness of gastrodia elata extract in preventing and treating parkinsonism | 中国农业科学院农产品加工研究所 | 2025-02-28 | — | — | CN | disclosed |
| CN-110551091-B | Asymmetric preparation method and application of 7-amino chroman compounds | 中国科学院上海有机化学研究所 | 2023-01-31 | — | — | CN | disclosed |
| CN-110551091-B | Asymmetric preparation method and application of 7-amino chroman compounds | 中国科学院上海有机化学研究所 | 2023-01-31 | — | — | CN | disclosed |
| CN-110551091-B | Asymmetric preparation method and application of 7-amino chroman compounds | 中国科学院上海有机化学研究所 | 2023-01-31 | — | — | CN | disclosed |
| WO-2022133303-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-06-23 | — | — | WO | disclosed |
| CN-110551091-A | Asymmetric preparation method and application of 7-amino chroman compounds | SHANGHAI INST ORGANIC CHEMISTRY CAS | 2019-12-10 | — | — | CN | disclosed |
| CN-110551091-A | Asymmetric preparation method and application of 7-amino chroman compounds | SHANGHAI INST ORGANIC CHEMISTRY CAS | 2019-12-10 | — | — | CN | disclosed |
| CN-110551091-A | Asymmetric preparation method and application of 7-amino chroman compounds | SHANGHAI INST ORGANIC CHEMISTRY CAS | 2019-12-10 | — | — | CN | disclosed |
| US-9776967-B2 | Carboxamide derivatives as pesticidal compounds | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-03 | — | — | US | disclosed |
| WO-2016125187-A1 | NOVEL QUINOLINE DERIVATIVES AND PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-11 | — | — | WO | disclosed |
| EP-1103554-B9 | Derivatives of dihydrofuro-(3,4-b)-quinolein-1-ones, process of préparation and phamaceutical compositions containing them | SERVIER LAB (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6548515-B1 | Use as anticancer agents | LES LABORATORIES SERVIER (FR) | 2003-04-15 | — | — | US | disclosed |
| EP-1103554-B1 | Derivatives of dihydrofuro-(3,4-b)-quinolein-1-ones, process of préparation and phamaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-12 | — | — | EP | disclosed |
| EP-1103554-A1 | Derivatives of dihydrofuro-(3,4-b)-quinolein-1-ones, process of préparation and phamaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-05-30 | — | — | EP | disclosed |