Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 8/20 | 0.78 |
| ▸ | TGM1 | P22735 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006624 | 0.89 | F13A1 (0.82) | F13A1TGM1CYP2C19MEP1BKMT2A | |
| SCHEMBL7007806 | 0.88 | F13A1 (1.00) | F13A1TGM1MAPK1 | |
| SCHEMBL7005912 | 0.87 | F13A1 (0.79) | F13A1TGM1 | |
| SCHEMBL7004923 | 0.86 | F13A1 (0.77) | F13A1TGM1 | |
| SCHEMBL7004156 | 0.86 | F13A1 (0.77) | F13A1TGM1 | |
| SCHEMBL7003304 | 0.84 | F13A1 (0.73) | F13A1TGM1CYP2C19 | |
| SCHEMBL7005909 | 0.83 | F13A1 (0.79) | F13A1TGM1 | |
| SCHEMBL7007216 | 0.83 | F13A1 (0.90) | F13A1TGM1 | |
| SCHEMBL7004951 | 0.83 | F13A1 (1.00) | F13A1TGM1KMT2A | |
| SCHEMBL7002927 | 0.82 | F13A1 (0.76) | F13A1TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1348710-A1 | Sulfonamide derivatives of 3-substituted imidazo[1,2-D]-1,2,4-thiadiazoles and 3-substituted-[1,2,4]thiadiazolo[4,5-A]benzimidazole as inhibitors of fibrin cross-linking and transglutaminases | Apotex Inc. (CA) | 2003-10-01 | — | — | EP | disclosed |