SCHEMBL7005547

SCHEMBL7005547

[CH2]c1cccc(-c2ccccc2)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
HNF4A P41235 1/20 0.53
ALDH1A1 P00352 3/20 0.50
HSD17B10 Q99714 2/20 0.50
BCL2L1 Q07817 2/20 0.50
HPGD P15428 1/20 0.50
BACE1 P56817 3/20 0.46
ALOX5 P09917 1/20 0.40
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
CYP2A6 P11509 1/20 0.39
MAPK1 P28482 1/20 0.39
PDE4B Q07343 3/20 0.38
PDE4A P27815 2/20 0.38
PDE4C Q08493 2/20 0.38
PDE4D Q08499 2/20 0.38
BCAT2 O15382 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60283 0.83 HDAC4 (0.65) HDAC4HDAC2HDAC8HDAC6HNF4A
SCHEMBL30605196 0.83 HDAC4 (0.65) HDAC4HDAC2HDAC8HDAC6HNF4A
SCHEMBL29065602 0.80 HDAC4 (0.62) HDAC4HDAC2HDAC8HDAC6HNF4A
SCHEMBL275842 0.80 HDAC4 (0.62) HDAC4HDAC2HDAC8HDAC6HNF4A
SCHEMBL30688232 0.80 HDAC4 (0.62) HDAC4HDAC2HDAC8HDAC6HNF4A
SCHEMBL30834671 0.80 HDAC4 (0.62) HDAC4HDAC2HDAC8HDAC6HNF4A
SCHEMBL8559182 0.80 HDAC4 (0.62) HDAC4HDAC2HDAC8HDAC6HNF4A
SCHEMBL9487300 0.80 HDAC4 (0.62) HDAC4HDAC2HDAC8HDAC6HNF4A
SCHEMBL3805586 0.80 HDAC4 (0.62) HDAC4HDAC2HDAC8HDAC6HNF4A
Phosphine SCHEMBL28208528 0.80 HDAC4 (0.62) HDAC4HDAC2HDAC8HDAC6HNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0169808-A2 UV-absorber compounds, method for their preparation and their use as image dyes in photographic materials for the silver dye-bleaching process ILFORD AG (CH) 1986-01-29 EP claimed
EP-3645297-A1 IMPROVED METHOD FOR THE PARTIAL COLOURING OF PLASTIC PARTS Covestro Deutschland AG (DE) 2020-05-06 EP disclosed
EP-1268382-A2 ALKOXYLATED PERFUMED ALCOHOLS AND THE USE THEREOF Henkel Kommanditgesellschaft auf Aktien (DE) 2003-01-02 EP disclosed
EP-1265980-A1 USE OF AROMATIC ALCOHOL ALXOXYLATES IN DETERGENTS AND COSMETIC FORMULATIONS Henkel Kommanditgesellschaft auf Aktien (DE) 2002-12-18 EP disclosed
WO-2001070661-A2 ALKOXYLATED PERFUMED ALCOHOLS AND THE USE THEREOF HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-09-27 WO disclosed
WO-2001070925-A1 USE OF AROMATIC ALCOHOL ALXOXYLATES IN DETERGENTS AND COSMETIC FORMULATIONS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-09-27 WO disclosed
WO-2001070384-A2 USE OF PERFUMED ALCOHOL ALKOXYLATES AS SOLUBILIZING AUXILIARY AGENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-09-27 WO disclosed
EP-0264051-A2 Derivatives of hydroxycarboxylic acids, method for their production and their application to heat and pressure sensitive recording materials BAYER AG (DE) 1988-04-20 EP disclosed
US-4701525-A Polyazo dyestuffs having high UV absorption CIBA-GEIGY AG (CH) 1987-10-20 US disclosed
US-4609609-A ULTRAVIOLET CIBA GEIGY AG (CH) 1986-09-02 US disclosed
EP-0169808-A2 UV-absorber compounds, method for their preparation and their use as image dyes in photographic materials for the silver dye-bleaching process ILFORD AG (CH) 1986-01-29 EP disclosed