Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 13/20 | 0.63 |
| ▸ | GRIK2 | Q13002 | 13/20 | 0.63 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.49 |
| ▸ | PAM | P19021 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1857645 | 0.84 | GRIK1 (0.60) | GRIK1GRIK2GRIK3PAM | |
| SCHEMBL1857647 | 0.84 | GRIK1 (0.60) | GRIK1GRIK2GRIK3PAM | |
| SCHEMBL16147768 | 0.83 | GRIK1 (0.49) | GRIK1GRIK2HTR2APAM | |
| SCHEMBL7003638 | 0.83 | GRIK1 (0.49) | GRIK1GRIK2HTR2APAM | |
| SCHEMBL16147766 | 0.83 | GRIK1 (0.49) | GRIK1GRIK2HTR2APAM | |
| SCHEMBL3252010 | 0.81 | GRIK1 (0.57) | GRIK1GRIK2HTR2AGRIK3 | |
| SCHEMBL3252009 | 0.81 | GRIK1 (0.57) | GRIK1GRIK2HTR2AGRIK3 | |
| SCHEMBL21987027 | 0.81 | GRIK1 (0.65) | GRIK1GRIK2HTR2AGRIK3PAM | |
| SCHEMBL21987028 | 0.81 | GRIK1 (0.65) | GRIK1GRIK2HTR2AGRIK3PAM | |
| SCHEMBL1716930 | 0.81 | GRIK1 (0.65) | GRIK1GRIK2HTR2AGRIK3PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347978-A1 | NOVEL SUBSTITUTED IMIDAZOTRIAZINONES AS PDE II-INHIBITORS | Bayer Aktiengesellschaft (DE) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002050078-A1 | NOVEL SUBSTITUTED IMIDAZOTRIAZINONES AS PDE II-INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-27 | — | — | WO | disclosed |