Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008821 | 0.92 | GNRHR (0.71) | GNRHR | |
| SCHEMBL7008230 | 0.92 | GNRHR (0.81) | GNRHR | |
| SCHEMBL7014054 | 0.91 | GNRHR (0.72) | GNRHR | |
| SCHEMBL5151063 | 0.90 | GNRHR (0.85) | GNRHR | |
| SCHEMBL7009012 | 0.89 | GNRHR (0.78) | GNRHR | |
| SCHEMBL7012944 | 0.88 | GNRHR (0.68) | GNRHR | |
| SCHEMBL7497714 | 0.88 | GNRHR (0.71) | GNRHR | |
| SCHEMBL7006641 | 0.88 | GNRHR (0.71) | GNRHR | |
| SCHEMBL7015424 | 0.88 | GNRHR (0.71) | GNRHR | |
| SCHEMBL7005385 | 0.87 | GNRHR (0.74) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756599-B1 | BICYCLIC THIOPHENE DERIVATIVES AND USE AS GONADOTROPIN RELEASING HORMONE ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-11-26 | — | — | EP | claimed |
| EP-0781774-B1 | Prolactin production inhibitory agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-07-31 | — | — | EP | claimed |
| US-8193252-B1 | Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders | Bayer Pharma AG (DE) | 2012-06-05 | — | — | US | disclosed |
| EP-1229906-A2 | MESOPROGESTINS FOR THE TREATMENT AND PREVENTION OF BENIGN HORMONE DEPENDENT GYNECOLOGICAL DISORDERS | Jenapharm GmbH & Co. KG (DE) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001015679-A2 | MESOPROGESTINS FOR THE TREATMENT AND PREVENTION OF BENIGN HORMONE DEPENDENT GYNECOLOGICAL DISORDERS | JENAPHARM GMBH & CO. KG (DE) | 2001-03-08 | — | — | WO | disclosed |
| EP-0877621-A1 | COMBINED PHARMACEUTICAL PREPARATION CONTAINING LHRH-ANALOGOUS SUBSTANCES AND ANTI-ESTROGENS FOR TREATING GYNAECOLOGICAL DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997027863-A1 | COMBINED PHARMACEUTICAL PREPARATION CONTAINING LHRH-ANALOGOUS SUBSTANCES AND ANTI-ESTROGENS FOR TREATING GYNAECOLOGICAL DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-08-07 | — | — | WO | disclosed |