SCHEMBL7006437

SCHEMBL7006437

C1=CNOC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8396732 1.00
SCHEMBL29086542 0.97
SCHEMBL29158521 0.97
SCHEMBL30088521 0.97
Water SCHEMBL8722365 0.97
Potassium SCHEMBL29704193 0.97
Charcoal, Activated SCHEMBL7974835 0.97
Water SCHEMBL1325514 0.97
Hydrochloric Acid SCHEMBL4017637 0.97
Hydrochloric Acid SCHEMBL7006678 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2003526654-A 2003-09-09 JP claimed
EP-1263414-A1 PHARMACEUTICAL COMPOSITIONS OF GLYCOGEN PHOSPHORYLASE INHIBITORS Pfizer Products Inc. (US) 2002-12-11 EP claimed
WO-2001068055-A1 PHARMACEUTICAL COMPOSITIONS OF GLYCOGEN PHOSPHORYLASE INHIBITORS PFIZER PRODUCTS INC. (US) 2001-09-20 WO claimed
US-5952322-A AMIDE-SUBSTITUTED BENZIMIDAZOLE, INDOLE DERIVATIVES PFIZER INC. (US) 1999-09-14 US claimed
CN-117940399-A Heteroaryl or aryl substituted bisphenol compounds and thermoplastic resins 三菱瓦斯化学株式会社 2024-04-26 CN disclosed
CN-112204028-B tetrahydro-1H-pyrazino [2,1-a ] isoindoloquinoline compounds for use in the treatment of autoimmune diseases 豪夫迈·罗氏有限公司 2023-12-29 CN disclosed
EP-4161937-A1 PYRIDO[2,3-B] [1,4] OXAZINES OR TETRAHYDROPYRIDO[2,3-B][1,4] OXAZEPINES AS IAP ANTAGONISTS BeiGene, Ltd. (KY) 2023-04-12 EP disclosed
CN-115066438-A ASGPR binding compounds for degrading extracellular proteins 阿维拉治疗公司 2022-09-16 CN disclosed
CN-114380845-A Heterocyclic-fused compound, pharmaceutical composition containing same, preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2022-04-22 CN disclosed
CN-112204028-A tetrahydro-1H-pyrazino [2,1-a ] isoindolyl quinoline compounds for the treatment of autoimmune diseases 豪夫迈·罗氏有限公司 2021-01-08 CN disclosed
CN-112020500-A Aminopyridine derivatives as inhibitors of phosphatidylinositol phosphokinase 拉文纳制药公司 2020-12-01 CN disclosed
CN-111936484-A Chromenopyridine derivatives as inhibitors of phosphatidylinositol phosphokinase 拉文纳制药公司 2020-11-13 CN disclosed
CN-109134438-B 1-phenazinyl (phenyl) (5-pyrimidinyl) methanol compound and preparation method and application thereof 长江大学 2020-10-09 CN disclosed
EP-1263414-A1 PHARMACEUTICAL COMPOSITIONS OF GLYCOGEN PHOSPHORYLASE INHIBITORS Pfizer Products Inc. (US) 2002-12-11 EP disclosed
WO-2001068055-A1 PHARMACEUTICAL COMPOSITIONS OF GLYCOGEN PHOSPHORYLASE INHIBITORS PFIZER PRODUCTS INC. (US) 2001-09-20 WO disclosed
US-5952322-A AMIDE-SUBSTITUTED BENZIMIDAZOLE, INDOLE DERIVATIVES PFIZER INC. (US) 1999-09-14 US disclosed
US-5863924-A Aryl pyrimidine derivatives SYNTEX (U.S.A.) INC. (US) 1999-01-26 US disclosed