SCHEMBL7006719

SCHEMBL7006719

CN(C)c1ccccc1Nc1ccc(N)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.58
KDM4E B2RXH2 3/20 0.58
ALOX15 P16050 3/20 0.58
TP53 P04637 2/20 0.58
APP P05067 1/20 0.58
HPGD P15428 1/20 0.58
SNCA P37840 1/20 0.58
BLM P54132 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
HSD17B10 Q99714 1/20 0.58
ALDH1A1 P00352 6/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
MAPK1 P28482 2/20 0.54
HTT P42858 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
CYP3A4 P08684 2/20 0.50
ALOX12 P18054 1/20 0.50
KDM1A O60341 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14127728 0.84 KDM1A (0.56) MAPTKDM4EALOX15TP53HPGD
SCHEMBL29624619 0.84 KDM1A (0.56) MAPTKDM4EALOX15TP53HPGD
SCHEMBL11731265 0.83 MAPT (0.56) MAPTKDM4ETP53HPGDBLM
SCHEMBL24776423 0.81 KDM1A (0.50) MAPTKDM4EALOX15HPGDHSD17B10
SCHEMBL7006260 0.80 MAPT (0.51) MAPTKDM4EALOX15TP53APP
SCHEMBL7007011 0.80 MAPT (0.48) MAPTKDM4EALOX15TP53APP
SCHEMBL3196135 0.80 KDM1A (0.58) MAPTKDM4ETP53SMN1; SMN2ALDH1A1
SCHEMBL30935911 0.80 KDM1A (0.58) MAPTKDM4ETP53SMN1; SMN2ALDH1A1
SCHEMBL31454751 0.80 MAPT (0.78) MAPTKDM4EALOX15TP53APP
SCHEMBL7007805 0.79 MAPT (0.55) MAPTKDM4EALOX15TP53APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0995786-B1 Electrochromic device NIPPON MITSUBISHI OIL CORP (JP) 2003-01-08 EP disclosed
US-6208452-B1 HAS AN ION CONDUCTIVE LAYER OBTAINED BY CURING A COMPOSITION COMPRISING A BIPYRIDINIUM COMPOUND, A SPECIFIC AMINE COMPOUND AND A PRECURSOR COMPONENT OF A POLYMERIC SOLID ELECTROLYTE DISPOSED BETWEEN TWO ELECTRICALLY CONDUCTIVE SUBSTRATES NIPPON MITSUBISHI OIL CORPORATION (JP) 2001-03-27 US disclosed
US-6203154-B1 MULTILAYER NIPPON MITSUBISHI OIL CORPORATION (JP) 2001-03-20 US disclosed
EP-1041425-A1 ELECTROCHROMIC ELEMENT Nippon Mitsubishi Oil Corporation (JP) 2000-10-04 EP disclosed
EP-0995786-A1 Electrochromic device Nippon Mitsubishi Oil Corporation (JP) 2000-04-26 EP disclosed
US-4971942-A Colorless basic chromogenic cye, divinyl compound, fluorane-type leuco dye JUJO PAPER CO., LTD. (JP) 1990-11-20 US disclosed