⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830712 | 0.79 | — | — | |
| SCHEMBL9830721 | 0.79 | — | — | |
| SCHEMBL9015530 | 0.72 | — | — | |
| SCHEMBL1171018 | 0.72 | — | — | |
| SCHEMBL14384895 | 0.72 | — | — | |
| SCHEMBL27709112 | 0.72 | — | — | |
| SCHEMBL972256 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL27646877 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL27889815 | 0.70 | — | — | |
| SCHEMBL3300019 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103228643-A | Benzazole derivatives as histamine H4 receptor ligands | BIOPROJET SOC CIV | 2013-07-31 | — | — | CN | claimed |
| CN-101870690-A | The prevention and the treatment that are substituted aryl and heteroaryl derivative and associated conditions thereof as metabolism regulators | ARENA PHARM INC | 2010-10-27 | — | — | CN | claimed |
| CN-1997640-A | Substituted aryl and heteroaryl derivatives as modulators of metabolism and the prevention and treatment of disorders related thereto | ARENA PHARM INC (US) | 2007-07-11 | — | — | CN | claimed |
| EP-0842180-B1 | PENAM SULFONES AS BETA-LACTAMASE INHIBITORS | NAEJA PHARMACEUTICAL INC (CA) | 2003-01-22 | — | — | EP | claimed |
| CN-107573275-A | Cinnamamide derivative | 日本脏器制药株式会社 | 2018-01-12 | — | — | CN | disclosed |
| CN-101668769-B | Novel tetrahydrocarbazole derivatives as ligands of g-protein coupled receptors | AETERNA ZENTARIS GMBH | 2014-07-02 | — | — | CN | disclosed |
| CN-103228643-A | Benzazole derivatives as histamine H4 receptor ligands | BIOPROJET SOC CIV | 2013-07-31 | — | — | CN | disclosed |
| CN-101870690-A | The prevention and the treatment that are substituted aryl and heteroaryl derivative and associated conditions thereof as metabolism regulators | ARENA PHARM INC | 2010-10-27 | — | — | CN | disclosed |
| CN-1997640-A | Substituted aryl and heteroaryl derivatives as modulators of metabolism and the prevention and treatment of disorders related thereto | ARENA PHARM INC (US) | 2007-07-11 | — | — | CN | disclosed |
| EP-1349852-A2 | 4-(HETERO)ARYL SUBSTITUTED INDOLINONES | Sugen, Inc. (US) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002055517-A2 | 4-(HETERO)ARYL SUBSTITUTED INDOLINONES | CUI JINGRONG (US) | 2002-07-18 | — | — | WO | disclosed |
| EP-1154774-A1 | QUINAZOLINE DERIVATIVES AS ANGIOGENESIS INHIBITORS | AstraZeneca AB (SE) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000047212-A1 | QUINAZOLINE DERIVATIVES AS ANGIOGENESIS INHIBITORS | ASTRAZENECA AB (SE) | 2000-08-17 | — | — | WO | disclosed |
| US-5608056-A | Substituted 3-pyrrolidinylthio-carbapenems as antimicrobial agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| WO-1993021186-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-28 | — | — | WO | disclosed |