Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007268 | 0.98 | FFAR1 (0.31) | FFAR1CPT2TDP1 | |
| SCHEMBL5705326 | 0.95 | FFAR1 (0.34) | FFAR1CPT2TDP1MAPTKMT2A | |
| SCHEMBL5705306 | 0.93 | FFAR1 (0.37) | FFAR1CPT2TDP1MAPTKMT2A | |
| SCHEMBL5705283 | 0.91 | — | — | |
| SCHEMBL7025017 | 0.87 | — | — | |
| SCHEMBL8898451 | 0.78 | TDP1 (0.39) | FFAR1CPT2TDP1MAPTKMT2A | |
| SCHEMBL7007273 | 0.77 | FFAR1 (0.33) | FFAR1CPT2TDP1 | |
| SCHEMBL8896237 | 0.77 | KMT2A (0.55) | FFAR1TDP1MAPTKMT2A | |
| SCHEMBL13302050 | 0.76 | FFAR1 (0.36) | FFAR1CPT2TDP1MAPTKMT2A | |
| SCHEMBL8896365 | 0.75 | KMT2A (0.52) | FFAR1TDP1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326822-A2 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2003-07-16 | — | — | EP | claimed |
| WO-2002030860-A2 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2002-04-18 | — | — | WO | claimed |
| WO-2002030860-A9 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS INC (US) | 2003-02-20 | — | — | WO | disclosed |