Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 19/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008700 | 1.00 | OPRL1 (0.70) | OPRL1OPRM1OPRK1KCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6494329 | 0.99 | OPRL1 (0.69) | OPRL1OPRM1OPRK1KCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6494946 | 0.99 | OPRL1 (0.69) | OPRL1OPRM1OPRK1KCNH2ALDH1A1 | |
| SCHEMBL7008710 | 0.96 | OPRL1 (0.77) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL7007146 | 0.96 | OPRL1 (0.77) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| Hydrochloric Acid SCHEMBL6494951 | 0.95 | OPRL1 (0.76) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| Hydrochloric Acid SCHEMBL6494335 | 0.95 | OPRL1 (0.76) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| Hydrochloric Acid SCHEMBL6494827 | 0.88 | OPRL1 (0.62) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| Hydrochloric Acid SCHEMBL6531302 | 0.87 | OPRL1 (0.67) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL6494958 | 0.87 | OPRL1 (0.91) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1342717-A1 | BENZIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-09-10 | — | — | EP | disclosed |