SCHEMBL7007829

SCHEMBL7007829

CC(C)N(c1cccc(-c2nccc3ccccc23)c1)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
MAPT P10636 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
KMT2A Q03164 2/20 0.43
GLA P06280 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GPR55 Q9Y2T6 1/20 0.41
MAOA P21397 1/20 0.39
CYP2A6 P11509 1/20 0.39
MAPK1 P28482 2/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
CASP1 P29466 1/20 0.39
CYP2C19 P33261 1/20 0.39
CASP7 P55210 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7004022 0.84 KDM4E (0.47) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL7007825 0.81 KDM4E (0.50) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL17449880 0.80 KDM4E (0.57) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL29607745 0.80 KDM4E (0.57) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL27551428 0.78 KDM4E (0.47) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL13327607 0.77 KDM4E (0.43) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL11976467 0.76 KMT2A (0.50) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL3141880 0.76 KDM4E (0.57) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL17426492 0.74 KDM4E (0.51) KDM4ENPC1RAB9AMAPTL3MBTL1
SCHEMBL11976498 0.74 KDM4E (0.55) KDM4ENPC1RAB9AMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012064499-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2012-05-18 WO disclosed