Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007498 | 0.93 | CYSLTR1 (0.51) | CYSLTR2CYSLTR1 | |
| SCHEMBL9818450 | 0.86 | CYSLTR1 (0.52) | CYSLTR2CYSLTR1 | |
| SCHEMBL9818398 | 0.85 | CYSLTR1 (0.47) | CYSLTR2CYSLTR1 | |
| SCHEMBL7011368 | 0.83 | CYSLTR1 (0.53) | CYSLTR2CYSLTR1 | |
| SCHEMBL9818505 | 0.81 | PDE10A (0.47) | CYSLTR2CYSLTR1 | |
| SCHEMBL7710931 | 0.79 | CYSLTR1 (0.53) | CYSLTR2CYSLTR1 | |
| SCHEMBL7716669 | 0.79 | CYSLTR1 (0.55) | CYSLTR2CYSLTR1 | |
| SCHEMBL7451857 | 0.78 | — | — | |
| SCHEMBL6089637 | 0.78 | CYSLTR1 (0.47) | CYSLTR2CYSLTR1 | |
| SCHEMBL7520309 | 0.78 | CYSLTR1 (0.50) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1267874-A2 | THERAPEUTIC USES OF PPAR MEDIATORS | Aventis Pharma Deutschland GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001066098-A2 | THERAPEUTIC USES OF PPAR MEDIATORS | AVENTIS PHARMA DEUTSCHLAND GMBH | 2001-09-13 | — | — | WO | disclosed |
| US-5059610-A | QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-10-22 | — | — | US | disclosed |
| US-4920132-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |