Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157822 | 0.88 | TTR (0.56) | MEN1KMT2AMAPTALDH1A1PDE7A | |
| SCHEMBL7004094 | 0.88 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL10409125 | 0.87 | POLB (0.56) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7007618 | 0.87 | MAPT (0.54) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL811068 | 0.84 | MAPT (0.56) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL7005180 | 0.84 | KMT2A (0.59) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL7024527 | 0.83 | MAPT (0.60) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL811412 | 0.82 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL1455427 | 0.82 | MAPT (0.62) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL10417341 | 0.81 | KMT2A (0.56) | MEN1KMT2ANPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0978506-B1 | 2-PHENOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-6156801-A | 2-phenoxyaniline derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0978506-A1 | 2-PHENOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2000-02-09 | — | — | EP | disclosed |