Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015485 | 0.95 | GNRHR (0.67) | GNRHRMEN1KMT2A | |
| SCHEMBL5149294 | 0.86 | GNRHR (0.83) | GNRHRMEN1KMT2A | |
| SCHEMBL7012789 | 0.85 | GNRHR (0.70) | GNRHRMEN1KMT2A | |
| SCHEMBL7009444 | 0.85 | GNRHR (0.77) | GNRHRMEN1KMT2A | |
| SCHEMBL7006717 | 0.85 | GNRHR (0.89) | GNRHRMEN1KMT2A | |
| SCHEMBL7015901 | 0.84 | GNRHR (1.00) | GNRHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7498171 | 0.84 | GNRHR (0.88) | GNRHRMEN1KMT2A | |
| SCHEMBL7017788 | 0.83 | GNRHR (0.80) | GNRHRMEN1KMT2A | |
| SCHEMBL7008671 | 0.83 | GNRHR (0.88) | GNRHRMEN1KMT2A | |
| SCHEMBL7101852 | 0.82 | GNRHR (0.82) | GNRHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756599-B1 | BICYCLIC THIOPHENE DERIVATIVES AND USE AS GONADOTROPIN RELEASING HORMONE ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-11-26 | — | — | EP | claimed |
| EP-0756599-B1 | BICYCLIC THIOPHENE DERIVATIVES AND USE AS GONADOTROPIN RELEASING HORMONE ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-11-26 | — | — | EP | disclosed |