Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.66 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008411 | 0.81 | HDAC1 (0.60) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL310002 | 0.80 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL310001 | 0.80 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL5683659 | 0.79 | HDAC1 (0.66) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL7094537 | 0.79 | HDAC1 (0.66) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL12487265 | 0.73 | HDAC1 (0.73) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL164803 | 0.73 | HDAC1 (0.73) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL3261129 | 0.73 | HDAC1 (0.73) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL31369764 | 0.72 | HDAC3 (0.54) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL23055056 | 0.69 | HDAC1 (0.59) | HDAC1HDAC3HDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318980-A2 | HYDROXAMATE DERIVATIVES USEFUL AS DEACETYLASE INHIBITORS | Novartis AG (CH) | 2003-06-18 | — | — | EP | claimed |
| WO-2002022577-A2 | HYDROXAMATE DERIVATIVES USEFUL AS DEACETYLASE INHIBITORS | NOVARTIS AG (CH) | 2002-03-21 | — | — | WO | claimed |