Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TOP2A | P11388 | 14/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 10/20 | 0.51 |
| ▸ | TOP1 | P11387 | 3/20 | 0.51 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006572 | 0.93 | KMT2A (0.53) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| SCHEMBL7007019 | 0.86 | KMT2A (0.77) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| Hydrochloric Acid SCHEMBL7007433 | 0.86 | KMT2A (0.76) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| SCHEMBL7008063 | 0.83 | KMT2A (0.69) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| SCHEMBL8482062 | 0.81 | TOP1 (0.59) | KMT2ATOP2ATOP2BTOP1GSK3B | |
| SCHEMBL7009374 | 0.81 | TOP1 (0.59) | KMT2ATOP2ATOP2BTOP1GSK3B | |
| SCHEMBL7013040 | 0.81 | KMT2A (0.69) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| SCHEMBL18313674 | 0.81 | KMT2A (0.66) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| SCHEMBL21440681 | 0.81 | KMT2A (0.66) | KMT2ATOP2ATOP2BTOP1EPHA2 | |
| SCHEMBL18313209 | 0.81 | KMT2A (0.66) | KMT2ATOP2ATOP2BTOP1EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787720-B1 | PYRIDONECARBOXYLATE DERIVATIVE OR SALT THEREOF AND ANTIBACTERIAL CONTAINING THE SAME AS ACTIVE INGREDIENT | WAKUNAGA SEIYAKU KK (JP) | 2003-07-16 | — | — | EP | disclosed |
| US-5910498-A | NOVEL COMPOUNDS HAVING REDUCED CYTOTOXICITY, PHOTOTOXICITY; TREATING BACTERIAL AND VIRAL INFECTIONS | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0787720-A1 | NOVEL PYRIDONECARBOXYLATE DERIVATIVE OR SALT THEREOF AND ANTIBACTERIAL CONTAINING THE SAME AS ACTIVE INGREDIENT | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-06 | — | — | EP | disclosed |