Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | CLK2 | P49760 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TOP2A | P11388 | 6/20 | 0.54 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007551 | 0.90 | TOP2A (0.52) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL7010011 | 0.90 | TOP2A (0.54) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL4987044 | 0.87 | KCNH2 (0.52) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL483223 | 0.82 | KDM4E (0.65) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL29393776 | 0.82 | KDM4E (0.65) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL7012229 | 0.82 | TOP2A (0.57) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL28424222 | 0.81 | KDM4E (0.64) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL541514 | 0.81 | KDM4E (0.64) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL541515 | 0.81 | KDM4E (0.64) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL7013345 | 0.81 | TOP2A (0.49) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |