SCHEMBL7008919

SCHEMBL7008919

CCOC(=O)CC(=O)c1cc(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MGAM O43451 1/20 0.44
GAA P10253 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
MIF P14174 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
HPGD P15428 1/20 0.40
NLRP3 Q96P20 1/20 0.39
MGLL Q99685 1/20 0.38
GPR35 Q9HC97 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
MAPT P10636 2/20 0.37
TSHR P16473 1/20 0.37
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
BAZ2B Q9UIF8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10616642 0.80 MEN1 (0.41) MEN1KMT2AKDM4EALDH1A1MGAM
SCHEMBL9328809 0.80 CYP4F2 (0.51) KMT2AKDM4EALDH1A1GAAMAPT
SCHEMBL30297970 0.78 MIF (0.43) MEN1KMT2AKDM4EALDH1A1MGAM
SCHEMBL28692264 0.78 MEN1 (0.45) MEN1KMT2AKDM4EALDH1A1MGAM
SCHEMBL30181088 0.78 MEN1 (0.42) MEN1KMT2AKDM4EALDH1A1MGAM
SCHEMBL30181504 0.78 MEN1 (0.42) MEN1KMT2AKDM4EALDH1A1MGAM
SCHEMBL7011856 0.78 MEN1 (0.42) MEN1KMT2AKDM4EALDH1A1MGAM
SCHEMBL19971534 0.78 MIF (0.43) MEN1KMT2AKDM4EALDH1A1MGAM
SCHEMBL29007819 0.78 MEN1 (0.42) MEN1KMT2AKDM4EALDH1A1MGAM
SCHEMBL8183324 0.77 MEN1 (0.44) MEN1KMT2AKDM4EALDH1A1MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0787720-B1 PYRIDONECARBOXYLATE DERIVATIVE OR SALT THEREOF AND ANTIBACTERIAL CONTAINING THE SAME AS ACTIVE INGREDIENT WAKUNAGA SEIYAKU KK (JP) 2003-07-16 EP disclosed
US-5910498-A NOVEL COMPOUNDS HAVING REDUCED CYTOTOXICITY, PHOTOTOXICITY; TREATING BACTERIAL AND VIRAL INFECTIONS WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1999-06-08 US disclosed
EP-0787720-A1 NOVEL PYRIDONECARBOXYLATE DERIVATIVE OR SALT THEREOF AND ANTIBACTERIAL CONTAINING THE SAME AS ACTIVE INGREDIENT WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1997-08-06 EP disclosed