Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 14/20 | 0.72 |
| ▸ | TOP2B | Q02880 | 14/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011715 | 0.92 | TOP2A (0.60) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL7008936 | 0.91 | TOP2A (0.59) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL7011028 | 0.89 | TOP2A (0.57) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL7009585 | 0.89 | TOP2A (0.57) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL7014412 | 0.89 | TOP2A (0.57) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL7013762 | 0.89 | TOP2A (0.57) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL8319164 | 0.89 | TOP2A (0.56) | TOP2ATOP2BALDH1A1POLB | |
| SCHEMBL7009753 | 0.89 | TOP2A (0.56) | TOP2ATOP2BALDH1A1POLB | |
| SCHEMBL7013089 | 0.87 | TOP2A (0.54) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL7010788 | 0.87 | TOP2A (0.54) | TOP2ATOP2BKCNH2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |