SCHEMBL7009296

SCHEMBL7009296

O=Cc1ccccc1-c1cccc(O)c1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.67
TRIM24 O15164 1/20 0.59
TRIM33 Q9UPN9 1/20 0.59
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
LMNA P02545 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
MEN1 O00255 1/20 0.46
THRB P10828 1/20 0.46
BLM P54132 1/20 0.46
KMT2A Q03164 1/20 0.46
MIF P14174 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12760781 0.85 TRIM24 (0.67) ERN1TRIM24TRIM33CA1CA2
SCHEMBL7009287 0.84 ERN1 (0.67) ERN1TRIM24TRIM33CA1CA2
SCHEMBL8342481 0.81 TRIM24 (0.55) ERN1TRIM24TRIM33CA1CA2
SCHEMBL31152506 0.81 ERN1 (0.67) ERN1TRIM24TRIM33CA1CA2
SCHEMBL16439936 0.81 ERN1 (0.67) ERN1TRIM24TRIM33CA1CA2
SCHEMBL36440 0.81 ERN1 (1.00) ERN1TRIM24TRIM33CA1CA2
SCHEMBL29407137 0.81 ERN1 (1.00) ERN1TRIM24TRIM33CA1CA2
SCHEMBL31649251 0.80 ERN1 (0.52) ERN1TRIM24TRIM33CA1CA2
SCHEMBL31649069 0.80 ERN1 (0.52) ERN1TRIM24TRIM33CA1CA2
SCHEMBL249552 0.80 KMT2A (0.71) ERN1TRIM24TRIM33LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110628013-A Bifunctional phosphorus-containing polyphenylene ether, and preparation method and application thereof 河北健馨生物科技有限公司 2019-12-31 CN disclosed
WO-2003106467-A1 CHIRAL CATALYST, PROCESS FOR PREPARING THE SAME AND ITS USE IN THE OXIDATIVE COUPLING OF NAPHTHOLS CHENGDU INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2003-12-24 WO disclosed
US-5789499-A RETAINING EFFECT OF ANTIFOULING AGENT IN A COATED POLYMERIZATION REACTOR MITSUI CHEMICALS, INC. (JP) 1998-08-04 US disclosed
CN-1114323-A Polymerization process of vinyl chloride MITSUI TOATSU CHEMICALS (JP) 1996-01-03 CN disclosed