Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004325 | 0.80 | APP (0.47) | — | |
| SCHEMBL5212805 | 0.79 | APP (0.54) | — | |
| SCHEMBL21382408 | 0.76 | NPC1 (0.62) | — | |
| SCHEMBL18012472 | 0.75 | KDR (0.55) | — | |
| SCHEMBL6285864 | 0.75 | BACE1 (0.65) | — | |
| SCHEMBL31631318 | 0.75 | BACE1 (0.65) | — | |
| SCHEMBL1680671 | 0.75 | MAOB (0.54) | MAOBPPARAMAOASCN9APARP10 | |
| SCHEMBL992837 | 0.74 | MAOB (1.00) | MAOBPARP10NR4A2 | |
| SCHEMBL29638127 | 0.74 | MAOB (1.00) | MAOBMAOAPARP10NR4A2 | |
| SCHEMBL1379497 | 0.74 | MAOB (1.00) | MAOBMAOAPARP10NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268427-A1 | AMINOPYRIDINES AND THEIR USE AS ANTICONVULSANTS AND SODIUM CHANNEL BLOCKERS | Cocensys, Inc. (US) | 2003-01-02 | — | — | EP | claimed |
| WO-2001074779-A1 | AMINOPYRIDINES AND THEIR USE AS ANTICONVULSANTS AND SODIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2001-10-11 | — | — | WO | claimed |
| EP-1268427-A1 | AMINOPYRIDINES AND THEIR USE AS ANTICONVULSANTS AND SODIUM CHANNEL BLOCKERS | Cocensys, Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001074779-A1 | AMINOPYRIDINES AND THEIR USE AS ANTICONVULSANTS AND SODIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2001-10-11 | — | — | WO | disclosed |