Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700824 | 0.75 | FFAR3 (0.33) | MAPK1NFKB1NFKB2RELAGAA | |
| SCHEMBL18821254 | 0.69 | CRBN (0.31) | — | |
| SCHEMBL5663490 | 0.67 | MAPK1 (0.36) | MAPK1 | |
| SCHEMBL3432699 | 0.67 | MAPT (0.32) | — | |
| SCHEMBL5722406 | 0.67 | FFAR3 (0.39) | MAPK1 | |
| SCHEMBL3646229 | 0.67 | GRM2 (0.43) | MAPK1 | |
| SCHEMBL25241773 | 0.66 | MAPK1 (0.34) | MAPK1KDM1A | |
| SCHEMBL27427641 | 0.66 | CYP4F2 (0.33) | — | |
| SCHEMBL21564990 | 0.65 | FFAR3 (0.37) | GAA | |
| SCHEMBL25641870 | 0.65 | CHRM2 (0.40) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1891689-A | Aliphatic nitrogen - containing 5 - membered ring compound | TANABE SEIYAKU CO (JP) | 2007-01-10 | — | — | CN | disclosed |
| CN-1257891-C | Nitrogenous five-membered ring compound | TANABE SEIYAKU CO (JP) | 2006-05-31 | — | — | CN | disclosed |
| CN-1468216-A | Nitrogenous five-membered ring compound | ������ҩ��ʽ���� | 2004-01-14 | — | — | CN | disclosed |
| EP-1325910-A1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2003-07-09 | — | — | EP | disclosed |
| EP-1323710-A1 | NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | Tanabe Seiyaku Co., Ltd. (JP) | 2003-07-02 | — | — | EP | disclosed |