Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5640660 | 0.90 | DPP4 (0.53) | DPP4ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL5639355 | 0.88 | DPP4 (0.53) | DPP4ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL5643124 | 0.88 | DPP4 (0.56) | DPP4ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL5641580 | 0.88 | DPP4 (0.56) | DPP4ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL5642037 | 0.87 | DPP4 (0.65) | DPP4ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL5640838 | 0.86 | DPP4 (0.54) | DPP4ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL5640954 | 0.86 | DPP4 (0.55) | DPP4ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL5641886 | 0.85 | DPP4 (0.59) | DPP4ALDH1A1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL5642039 | 0.85 | DPP4 (0.68) | DPP4ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL5641838 | 0.84 | DPP4 (0.56) | DPP4ALDH1A1LMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301187-A2 | HETEROCYCLIC COMPOUNDS, WHICH ARE INHIBITORS OF THE ENZYME DPP-IV | NOVO NORDISK A/S (DK) | 2003-04-16 | — | — | EP | claimed |
| WO-2002002560-A2 | PURINE-2,6-DIONES WHICH ARE INHIBITORS OF THE ENZYME DIPEPTIDYL PEPTIDASE IV (DPP-IV) | NOVO NORDISK A/S (DK) | 2002-01-10 | — | — | WO | claimed |