Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008554 | 0.91 | STAT3 (0.49) | NPC1ALDH1A1MAPTLMNASTAT3 | |
| SCHEMBL7008195 | 0.86 | STAT3 (0.52) | NPC1ALDH1A1MAPTLMNASTAT3 | |
| SCHEMBL7008567 | 0.85 | NPC1 (0.56) | NPC1ALDH1A1MAPTLMNASTAT3 | |
| SCHEMBL7006908 | 0.85 | NPC1 (0.52) | NPC1ALDH1A1MAPTLMNASTAT3 | |
| SCHEMBL7008542 | 0.85 | STAT3 (0.51) | NPC1ALDH1A1MAPTLMNASTAT3 | |
| SCHEMBL7007126 | 0.84 | STAT3 (0.49) | NPC1ALDH1A1MAPTLMNASTAT3 | |
| SCHEMBL7005352 | 0.82 | STAT3 (0.51) | NPC1ALDH1A1MAPTLMNASTAT3 | |
| SCHEMBL7011166 | 0.82 | NPC1 (0.56) | NPC1ALDH1A1MAPTLMNASTAT3 | |
| SCHEMBL19728743 | 0.81 | STAT3 (0.47) | NPC1ALDH1A1MAPTLMNASTAT3 | |
| SCHEMBL7009131 | 0.81 | STAT3 (0.53) | ALDH1A1LMNASTAT3POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945435-B1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMA CO LTD (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-6136823-A | BACTERICIDES OR VIRICIDES | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0945435-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |