Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973862 | 0.88 | DPP4 (0.57) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL6843750 | 0.85 | DPP4 (0.48) | DPP4ALDH1A1LMNAMAPTTSHR | |
| Trifluoroacetic Acid SCHEMBL3969598 | 0.84 | DPP4 (0.53) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL6843026 | 0.81 | DPP4 (0.48) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL6838812 | 0.79 | DPP4 (0.53) | DPP4ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL6838716 | 0.79 | DPP4 (0.53) | DPP4ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL6843652 | 0.79 | DPP4 (0.42) | DPP4ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL3970965 | 0.79 | DPP4 (0.51) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL3975531 | 0.79 | DPP4 (0.51) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL6843487 | 0.78 | DPP4 (0.54) | DPP4ALDH1A1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122228-A1 | New purine derivatives, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122228-A1 | New purine derivatives, the preparation thereof and their use as pharmaceutical compositions | DPP4, DPP7, DPP3 | DPP4 1/4885L3MBTL1 3258/4885GAA 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.