Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 11/20 | 0.77 |
| ▸ | TGM1 | P22735 | 4/20 | 0.77 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005235 | 0.87 | F13A1 (1.00) | F13A1TGM1NPY5RALDH1A1KMT2A | |
| SCHEMBL7012245 | 0.86 | F13A1 (0.98) | F13A1TGM1NPY5RALDH1A1KMT2A | |
| SCHEMBL7003647 | 0.86 | F13A1 (1.00) | F13A1TGM1NPY5RALDH1A1KMT2A | |
| SCHEMBL7004147 | 0.85 | F13A1 (1.00) | F13A1TGM1NPY5RALDH1A1KMT2A | |
| SCHEMBL7004197 | 0.83 | F13A1 (0.84) | F13A1TGM1NPY5RALDH1A1KMT2A | |
| SCHEMBL7006324 | 0.80 | F13A1 (1.00) | F13A1TGM1NPY5RALDH1A1KMT2A | |
| SCHEMBL7009553 | 0.77 | F13A1 (0.78) | F13A1TGM1NPY5RALDH1A1KMT2A | |
| SCHEMBL7003758 | 0.74 | F13A1 (0.76) | F13A1TGM1KMT2AMEN1 | |
| SCHEMBL7004816 | 0.73 | F13A1 (0.67) | F13A1TGM1KMT2AMEN1 | |
| SCHEMBL7009684 | 0.71 | F13A1 (0.65) | F13A1TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1348710-A1 | Sulfonamide derivatives of 3-substituted imidazo[1,2-D]-1,2,4-thiadiazoles and 3-substituted-[1,2,4]thiadiazolo[4,5-A]benzimidazole as inhibitors of fibrin cross-linking and transglutaminases | Apotex Inc. (CA) | 2003-10-01 | — | — | EP | disclosed |