Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10537694 | 0.84 | MEN1 (0.61) | MEN1KMT2AKDM4EHSD17B10HPGD | |
| SCHEMBL7017825 | 0.84 | MEN1 (0.45) | MEN1KMT2AKDM4EHSD17B10HPGD | |
| SCHEMBL7012969 | 0.84 | MEN1 (0.45) | MEN1KMT2AKDM4EHSD17B10HPGD | |
| SCHEMBL7019146 | 0.84 | MEN1 (0.45) | MEN1KMT2AKDM4EHSD17B10HPGD | |
| SCHEMBL7020642 | 0.83 | MEN1 (0.44) | MEN1KMT2AKDM4EHSD17B10HPGD | |
| SCHEMBL7015364 | 0.83 | TRPV1 (0.43) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL7013922 | 0.82 | KMT2A (0.43) | MEN1KMT2AKDM4EHSD17B10HPGD | |
| SCHEMBL7014110 | 0.82 | MEN1 (0.43) | MEN1KMT2AKDM4EHSD17B10HPGD | |
| SCHEMBL7016565 | 0.81 | MEN1 (0.42) | MEN1KMT2AKDM4EHSD17B10HPGD | |
| SCHEMBL7011324 | 0.81 | MEN1 (0.42) | MEN1KMT2AKDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |