⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214086 | 0.79 | — | — | |
| SCHEMBL21594749 | 0.77 | — | — | |
| SCHEMBL13670068 | 0.77 | MAPT (0.30) | — | |
| SCHEMBL23250817 | 0.77 | — | — | |
| SCHEMBL6426169 | 0.75 | MAPT (0.33) | — | |
| SCHEMBL29140505 | 0.75 | MAPT (0.33) | — | |
| SCHEMBL358076 | 0.75 | — | — | |
| SCHEMBL22036438 | 0.75 | MAPT (0.41) | — | |
| SCHEMBL8978 | 0.73 | — | — | |
| SCHEMBL2715059 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355706-A1 | METHYLENEDIOXYBENZO [I] PHENANTHRIDINE DERIVATIVES USED TO TREAT CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-12-14 | — | — | US | disclosed |
| US-20170355706-A1 | METHYLENEDIOXYBENZO [I] PHENANTHRIDINE DERIVATIVES USED TO TREAT CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-12-14 | — | — | US | disclosed |
| US-9562051-B2 | Methylenedioxybenzo [I] phenanthridine derivatives used to treat cancer | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-02-07 | — | — | US | disclosed |
| CN-106317369-A | Aqueous polyurethane resin dispersion and use thereof | 宇部兴产株式会社 | 2017-01-11 | — | — | CN | disclosed |
| EP-1368324-A1 | QUINAZOLINES AS MMP-13 INHIBITORS | Warner-Lambert Company LLC (US) | 2003-12-10 | — | — | EP | disclosed |
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | ANDRIANJARA CHARLES (FR) | 2002-12-19 | — | — | US | disclosed |
| EP-0672446-B1 | Method for the removal of hydrogen sulfide present in gases | KANSAI ELECTRIC POWER CO (JP) | 2002-11-13 | — | — | EP | disclosed |
| WO-2002064572-A1 | QUINAZOLINES AS MMP-13 INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | disclosed |
| CN-1069551-C | Method for the removal of hydrogen sulfide present in gases | KANSAI ELECTRIC POWER CO (JP) | 2001-08-15 | — | — | CN | disclosed |
| US-5750083-A | USING AQUEOUS SOLUTION OF TRIETHYLENEDIAMINE | THE KANSAI ELECTRIC POWER CO., INC. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5609840-A | CONTACTING WITH TERTIARY DIALKYLHYDROXYALKYLAMINE; ABSORPTION | THE KANSAI ELECTRIC POWER CO., INC. (JP) | 1997-03-11 | — | — | US | disclosed |
| CN-1125158-A | Method for the removal of hydrogen sulfide present in gases | KANSAI ELECTRIC POWER CO (JP) | 1996-06-26 | — | — | CN | disclosed |
| EP-0672446-A2 | Method for the removal of hydrogen sulfide present in gases | THE KANSAI ELECTRIC POWER CO., INC. (JP) | 1995-09-20 | — | — | EP | disclosed |