Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 6/20 | 0.50 |
| ▸ | JAK3 | P52333 | 6/20 | 0.50 |
| ▸ | JAK1 | P23458 | 4/20 | 0.50 |
| ▸ | TTK | P33981 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 12/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016488 | 0.92 | JAK2 (0.48) | JAK2JAK3JAK1TTKNPY1R | |
| SCHEMBL7014469 | 0.89 | JAK3 (0.47) | JAK2JAK3JAK1TTKNPY1R | |
| SCHEMBL7016700 | 0.88 | JAK2 (0.45) | JAK2JAK3JAK1TTKNPY1R | |
| SCHEMBL7016400 | 0.88 | JAK2 (0.47) | JAK2JAK3JAK1TTKNPY1R | |
| SCHEMBL7019525 | 0.87 | JAK2 (0.44) | JAK2JAK3JAK1TTKNPY1R | |
| SCHEMBL7013408 | 0.87 | JAK2 (0.46) | JAK2JAK3JAK1TTKNPY1R | |
| SCHEMBL7018604 | 0.87 | JAK2 (0.46) | JAK2JAK3JAK1TTKNPY1R | |
| SCHEMBL7019795 | 0.87 | JAK2 (0.46) | JAK2JAK3JAK1TTKNPY1R | |
| SCHEMBL8057456 | 0.87 | NPY1R (0.49) | JAK2JAK3JAK1TTKNPY1R | |
| SCHEMBL7018375 | 0.86 | NPY1R (0.47) | JAK2JAK3JAK1TTKNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |