Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569460 | 0.89 | GNRHR (0.78) | GNRHR | |
| SCHEMBL7011581 | 0.89 | GNRHR (1.00) | GNRHR | |
| Hydrochloric Acid SCHEMBL7497443 | 0.89 | GNRHR (0.81) | GNRHR | |
| SCHEMBL7008161 | 0.89 | GNRHR (0.81) | GNRHR | |
| Hydrochloric Acid SCHEMBL7493979 | 0.89 | GNRHR (0.77) | GNRHR | |
| SCHEMBL7009882 | 0.88 | GNRHR (0.75) | GNRHR | |
| Hydrochloric Acid SCHEMBL7500013 | 0.88 | GNRHR (0.98) | GNRHR | |
| SCHEMBL7006776 | 0.87 | GNRHR (0.73) | GNRHR | |
| Hydrochloric Acid SCHEMBL8165522 | 0.87 | GNRHR (0.79) | GNRHR | |
| SCHEMBL7011587 | 0.87 | GNRHR (1.00) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756599-B1 | BICYCLIC THIOPHENE DERIVATIVES AND USE AS GONADOTROPIN RELEASING HORMONE ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-11-26 | — | — | EP | claimed |
| EP-0756599-B1 | BICYCLIC THIOPHENE DERIVATIVES AND USE AS GONADOTROPIN RELEASING HORMONE ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-11-26 | — | — | EP | disclosed |