Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359817 | 0.90 | HTR2A (0.59) | HTR2AHTR1ADRD2TSHRCHRNA7 | |
| SCHEMBL5364879 | 0.90 | HTR2A (0.59) | HTR2AHTR1ADRD2TSHRCHRNA7 | |
| SCHEMBL5359826 | 0.90 | HTR2A (0.59) | HTR2AHTR1ADRD2TSHRCHRNA7 | |
| SCHEMBL5359086 | 0.88 | HTR2A (0.61) | HTR2AHTR1ADRD2TSHRUSP2 | |
| SCHEMBL5375200 | 0.88 | HTR2A (0.61) | HTR2AHTR1ADRD2TSHRUSP2 | |
| SCHEMBL5368375 | 0.88 | HTR2A (0.72) | HTR2AHTR1ADRD2KCNH2 | |
| SCHEMBL5359089 | 0.88 | HTR2A (0.61) | HTR2AHTR1ADRD2TSHRUSP2 | |
| SCHEMBL5368366 | 0.88 | HTR2A (0.72) | HTR2AHTR1ADRD2KCNH2 | |
| Hydrochloric Acid SCHEMBL5367657 | 0.87 | HTR2A (0.60) | HTR2AHTR1ADRD2TSHR | |
| Hydrochloric Acid SCHEMBL5367650 | 0.87 | HTR2A (0.60) | HTR2AHTR1ADRD2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216244-B1 | Benzisoxazolyl-, pyridoisoxazolyl- and benzthienyl-phenoxy derivatives useful as D4 antagonists | AVENTIS PHARMA INC (US) | 2003-08-13 | — | — | EP | claimed |