Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 16/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009294 | 0.91 | NPY1R (0.55) | NPY1RKCNH2 | |
| SCHEMBL7019032 | 0.91 | NPY1R (0.55) | NPY1RKCNH2 | |
| SCHEMBL7015352 | 0.89 | NPY1R (0.53) | NPY1RKCNH2 | |
| SCHEMBL7013811 | 0.87 | NPY1R (0.51) | NPY1RKCNH2 | |
| SCHEMBL12946434 | 0.87 | NPY1R (0.51) | NPY1RKCNH2 | |
| SCHEMBL7016178 | 0.86 | NPY1R (0.50) | NPY1R | |
| SCHEMBL7017636 | 0.86 | NPY1R (0.50) | NPY1RKCNH2 | |
| SCHEMBL7011726 | 0.85 | NPY1R (0.51) | NPY1RKCNH2 | |
| SCHEMBL7096763 | 0.84 | NPY1R (0.52) | NPY1RKCNH2 | |
| SCHEMBL7018732 | 0.84 | NPY1R (0.48) | NPY1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |