SCHEMBL7012989

SCHEMBL7012989

CC(S)C([NH])=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1679979 0.75
SCHEMBL23067 0.75
SCHEMBL8748977 0.72
SCHEMBL3923253 0.72
SCHEMBL98764 0.72
SCHEMBL946721 0.72 TDP1 (0.53)
SCHEMBL641605 0.72
SCHEMBL15388812 0.72
SCHEMBL2390431 0.72
SCHEMBL11443139 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1172364-B1 A process for the preparation of 2-phenyl-imidazo[1,2-A]pyridine-3-acetamides DINAMITE DIPHARMA S P A IN ABB (IT) 2003-04-23 EP disclosed
US-6384226-B2 REACTING 2-PHENYL-IMIDAZOLO(1,2-A)PYRIDINE WITH OXALIC ACID ESTER; REDUCTION; AMIDATION DINAMITE DIPHARMA S.P.A. (IT) 2002-05-07 US disclosed
US-20020019528-A1 Process for the preparation of 2-phenyl-imidazo [1, 2-a] pyridine-3-acetamides DINAMITE DIPHARMA S.P.A. 2002-02-14 US disclosed
EP-1172364-A1 A process for the preparation of 2-phenyl-imidazo[1,2-A]pyridine-3-acetamides Dinamite Dipharma S.p.A. (in abbreviated form Dipharma S.p.A.) (IT) 2002-01-16 EP disclosed
EP-0610179-A1 TARGET SPECIFIC ANTIBODY-SUPERANTIGEN CONJUGATES AND THEIR PREPARATION. KABI PHARMACIA AB (SE) 1994-08-17 EP disclosed
US-4286089-A BACTERICIDES SMITHKLINE CORPORATION (US) 1981-08-25 US disclosed
EP-0000645-B1 ISOPENICILLINS, PROCESSES FOR THEIR PREPARATION, AND COMPOSITIONS CONTAINING THEM SMITHKLINE BECKMAN CORPORATION (US) 1981-01-28 EP disclosed
US-4220644-A BACTERICIDES SMITHKLINE CORPORATION (US) 1980-09-02 US disclosed