Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469716 | 0.89 | TDP1 (0.45) | MAPTTDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL28369479 | 0.76 | TDP1 (0.42) | MAPTTDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL2243721 | 0.73 | MEN1 (0.48) | MAPTTDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL6688479 | 0.73 | MAPT (0.51) | MAPTTDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL31180267 | 0.73 | MAPT (0.51) | MAPTTDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL31207333 | 0.73 | MEN1 (0.48) | MAPTTDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL4689264 | 0.71 | MAPT (0.50) | MAPTTDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL28327167 | 0.71 | TDP1 (0.41) | MAPTTDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL9452622 | 0.71 | MAPT (0.47) | MAPTTDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL30503607 | 0.71 | MAPT (0.47) | MAPTTDP1TSHRSMN1; SMN2GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100343225-C | Process for producing 5-nitro-3,4-dihydro-1(2h)-naphthalinone, 1-5-naphthalenediamine and 1,5-naphthalene diisocyanate | BAYER AG (DE) | 2007-10-17 | — | — | CN | claimed |
| CN-1467195-A | Process for producing 5-nitro-3,4-dihydro-1(2h)-naphthalinone, 1-5-naphthalenediamine and 1,5-naphthalene diisocyanate | — | 2004-01-14 | — | — | CN | claimed |
| CN-100343225-C | Process for producing 5-nitro-3,4-dihydro-1(2h)-naphthalinone, 1-5-naphthalenediamine and 1,5-naphthalene diisocyanate | BAYER AG (DE) | 2007-10-17 | — | — | CN | disclosed |
| CN-1467195-A | Process for producing 5-nitro-3,4-dihydro-1(2h)-naphthalinone, 1-5-naphthalenediamine and 1,5-naphthalene diisocyanate | — | 2004-01-14 | — | — | CN | disclosed |
| EP-1345888-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002051792-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-04 | — | — | WO | disclosed |